KAS is pleased to announce issuance of US Patent No. 8,999,682 entitled MANIPULATION OF GENES OF THE MEVALONATE AND ISOPRENOID PATHWAYS TO CREATE NOVEL TRAITS IN TRANSGENIC ORGANISMS granted to KAS on April 7, 2015.
This is valuable to make any number of industrially useful and high-value compounds including flavors, fragrances, rubber, pigments, and anti-oxidants using cell cultures. Claims are directed towards a transformed bacterial cell, plant cell, or microalgae cell that synthesizes an increased amount of isoprenoid or an isoprenoid precursors including isopentenyl pyrophosphate (IPP) and dimethylallyl diphosphate (DMAPP) via a mevalonate pathway and including IPP isomerase.
It complements US 7,129,392 entitled MATERIALS AND METHODS FOR INCREASING ISOPRENOID PRODUCTION IN CELLS and granted to KAS on October 31, 2006 and also co-owned with Danisco. KAS has full freedom to operate and license these technologies.
These technologies are available for licensing. Potential licensees would be those companies interested in synthetic rubber production and isoprenes, as well as companies commercializing monoterpenes, sesquiterpenes, diterpenes, triterpenes, tetraterpenes, and steroids.